Rheumatological manifestations of haematological diseases.

In a review published in 1983, an attempt was made to highlight the rheumatological aspects of diseases generally regarded as haematological in origin.' Since then, a variety of reports have served to strengthen the links between these two areas of medicine. In this review, we consider these more recent reports and focus on patient presentation, advances in treatment, and knowledge of underlying mechanisms. Epidemiological data are reviewed and, in particular, we speculate on the possible immunological mechanisms common to lymphoproliferative malignancy and autoimmune disease.